We develop a 3D hydrodynamical code written in C programming language to study the expansion of supernova remnants (SNRs) in the surrounding medium.It is based on the MUSCL-Hancock finite volume scheme with the HLLC Riemann solver.The code initiates the supernova remnant already in the Sedov phase and simulates hydrodynamics of the subsequent remna
Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular carcinoma
IntroductionHepatocellular carcinoma (HCC) patients at advanced stages receive immunotherapy or treatment with tyrosine kinase inhibitors (TKIs) such as Sorafenib (Sora) or Lenvatinib in frontline as well as Regorafenib (Rego) or Cabozantinib in second-line.A major hindrance of TKI therapies is the development of resistance, which renders drug trea
Traumatic Subarachnoid Hemorrhage Resulting from Posterior Communicating Artery Rupture
Jiha Kim,1,2 Seung Jin Lee1,2 1Department of Neurosurgery, Kangwon National University School of Medicine, Chuncheon-Si, Gangwon-Do, South Korea; 2Department of Neurosurgery, Kangwon National University Hospital, Chuncheon-Si, Gangwon-Do, South KoreaCorrespondence: Jiha KimDepartment of Neurosurgery, Kangwon National University School of Medicine,